{"product_id":"mitosis-jonathan-pines-9781621821359","title":"Mitosis","description":"Virtually every cell in a living organism contains an identical set of chromosomes thanks to mitosis, a complex process involving hundreds of proteins and regulatory steps that ensures duplicated chromosomes are segregated equally into each daughter cell when a cell divides. Errors in this process can lead to genomic instability and are associated with cancer and other diseases. \u003cp\u003e\u003c\/p\u003eWritten and edited by experts in the field, this collection from \u003cem\u003eCold Spring Harbor Perspectives in Biology \u003c\/em\u003ecovers both historical and recent developments in our understanding of mitosis and its regulation. The contributors describe how sister chromatids attach to one another and to the spindle apparatus; how the spindle microtubules nucleate, elongate, pause, and shrink; and how kinetochores and centrosomes serve as anchor and control points. They also survey the biochemical machinery that coordinates the three main regulatory stages-entry into mitosis, sister chromatid separation, and mitotic exit-in both space and time. \u003cp\u003e\u003c\/p\u003eThe cellular changes that occur during cytokinesis are also reviewed in detail, as are the key differences between mitosis and meiosis. This volume will serve as a valuable reference for all cell and molecular biologists interested in this dramatic phase of the cell cycle.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Jonathan Pines\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 1621821358\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9781621821359\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Cold Spring Harbor Laboratory Press\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 03\/31\/2015\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 200\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Paperback\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 1.10lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 9.90h x 7.00w x 0.50d","brand":"Jonathan Pines","offers":[{"title":"Paperback","offer_id":44919988224255,"sku":"9781621821359","price":21.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_fa9e9fad-4e9a-47ce-8889-984bcd7c67af.jpg?v=1710359911","url":"https:\/\/www.whiterainbookhouse.com\/products\/mitosis-jonathan-pines-9781621821359","provider":"WR Book House","version":"1.0","type":"link"}