{"product_id":"molecular-approaches-to-heart-failure-gerd-hasenfuss-9783798512368","title":"Molecular Approaches to Heart Failure Therapy","description":"Alterations in excitation-contraction coupling and potential gene thrapy targets in failing human hearts.- Cardiac overexpression of  -adrenergic receptors.- Genetic approaches to elucidate the regulatory role of phospholamban in the heart-. Manipulation of SERCA2a in the heart by gene transfer-. Changing the cardiac calcium transient: SERCA2 overexpression versus phospholamban inhibition.- Adenovirus-mediated gene transfer of SERCA isoforms.- Overexpression of FKBP12.6 to influenxe SR function.- Adenovirus-mediated myocardial gene therapy.- Adenovirus-mediated transfection of multicellular cardiac preparations.- Myocardial-specific gene delivery.- Transfection studies using a new cardiac 3D gel system.- Cellular mechanisms of cardiac arrhythmias - do they play a role in heart failure?.- Potassium channel overexpression.- Mechanisms and relevance of apoptosis.- Strategies to prevent apoptosis.- Neurohumoral modulation of metalloproeinases in cardiac failure: impact on remodeling.- Oxidative stress in heart failure.- Modulation of cardiac function by essential myosin light chains in health and disease.- Mycardial infarction, infarct repair, and strategies for muscle regeneration.- Cardiomyocytes can induce rhythmic contraction of skeletal muscle cells. Potenial use for infarct repair.- Strategies to identify cardimyocyte xell cycle regulatory genes.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Gerd Hasenfuss,Eduardo Marban\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 3798512361\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9783798512368\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Steinkopff-Verlag Darmstadt\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 09\/06\/2000\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 372\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Hardcover\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 1.53lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 9.21h x 6.14w x 0.88d","brand":"Gerd Hasenfuss","offers":[{"title":"Hardcover","offer_id":48136987476223,"sku":"9783798512368","price":119.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_6636a142-267c-43f4-bc8e-822cc2c7c499.jpg?v=1770165790","url":"https:\/\/www.whiterainbookhouse.com\/products\/molecular-approaches-to-heart-failure-gerd-hasenfuss-9783798512368","provider":"WR Book House","version":"1.0","type":"link"}