{"product_id":"molecules-engineered-against-oncogenic-proteins-e-j-corey-9781394207084","title":"Molecules Engineered Against Oncogenic Proteins and Cancer: Discovery, Design, and Development","description":"\u003cb\u003eMolecules Engineered Against Oncogenic Proteins and Cancer\u003c\/b\u003e \u003cp\u003e\u003cb\u003eA comprehensive review of the latest molecular advances in cancer treatment\u003c\/b\u003e \u003c\/p\u003e\u003cp\u003eFeaturing 91 total small molecule kinase\/KRAS inhibitors, 80 of which are FDA-approved, \u003ci\u003eMolecules Engineered Against Oncogenic Proteins and Cancer\u003c\/i\u003e documents the recent scientific advances that have transformed one of medicine's most challenging areas--cancer treatment. Most of these inhibitors specifically block oncogene-induced carcinogenic proteins with results that have dramatically advanced the treatment of cancer. In addition, the structural formulas of more than 100 kinase\/KRAS inhibitors in clinical trials are presented. \u003c\/p\u003e\u003cp\u003eWith a very well-known chemist as an author, \u003ci\u003eMolecules Engineered Against Oncogenic Proteins and Cancer\u003c\/i\u003e includes information on: \u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eEach molecule's structure, function of the kinase target and relevance to cancer, the drug discovery process, and molecular details of drug action\u003c\/li\u003e \u003cli\u003eMutated protein kinases as oncoproteins and targets for inhibition, along with the details of discovery for each antitumor antikinase agent\u003c\/li\u003e \u003cli\u003eHistory of oncoprotein inhibitors and their role in advancing the treatment and understanding of cancer\u003c\/li\u003e \u003cli\u003eThe discovery process as a whole, effective strategies for innovation, ongoing challenges, and a glimpse of the future of the field\u003c\/li\u003e\n\u003c\/ul\u003e \u003cp\u003eCombining the most significant recent discoveries in a unique and useful way, \u003ci\u003eMolecules Engineered Against Oncogenic Proteins and Cancer\u003c\/i\u003e is an essential resource for researchers and students in bioscience, medicine, chemistry, and oncology as well as for those at industrial companies involved in therapeutic discovery.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e E. J. Corey, Yong-Jin Wu\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 1394207085\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9781394207084\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Wiley\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 09\/06\/2023\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 400\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Hardcover\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 2.95lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 10.94h x 8.50w x 0.71d\u003c\/p\u003e","brand":"E. J. Corey","offers":[{"title":"Hardcover","offer_id":44121636831487,"sku":"9781394207084","price":175.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_766ffd60-f40d-4d50-b806-2324ffdfb0ef.jpg?v=1687420745","url":"https:\/\/www.whiterainbookhouse.com\/products\/molecules-engineered-against-oncogenic-proteins-e-j-corey-9781394207084","provider":"WR Book House","version":"1.0","type":"link"}