{"product_id":"oligonucleotide-synthesis-piet-herdewijn-9781588292339","title":"Oligonucleotide Synthesis: Methods and Applications","description":"A collection of powerful new techniques for oligonucleotide synthesis and for the use of modified oligonucleotides in biotechnology. Among the protocol highlights are a novel two-step process that yields a high purity, less costly, DNA, the synthesis of phosphorothioates using new sulfur transfer agents, the synthesis of LNA, peptide conjugation methods to improve cellular delivery and cell-specific targeting, and triple helix formation. The applications include using molecular beacons to monitor the PCR amplification process, nuclease footprinting to study the sequence-selective binding of small molecules of DNA, nucleic acid libraries, and the use of small interference RNA (siRNA) as an inhibitor of gene expression.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Piet Herdewijn\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 1588292339\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9781588292339\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Humana\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 09\/01\/2004\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 436\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Hardcover\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 1.87lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 9.14h x 14.36w x 1.17d\u003cbr\u003e\u003cbr\u003e\u003cb\u003eReview Citation(s): \u003c\/b\u003e\u003cbr\u003e\u003ci\u003eScitech Book News\u003c\/i\u003e 12\/01\/2004 pg. 73","brand":"Piet Herdewijn","offers":[{"title":"Hardcover","offer_id":43939819520255,"sku":"9781588292339","price":199.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/products\/img_7a2fe3b3-ea35-435b-9c0d-3152ceaebe70.jpg?v=1681443675","url":"https:\/\/www.whiterainbookhouse.com\/products\/oligonucleotide-synthesis-piet-herdewijn-9781588292339","provider":"WR Book House","version":"1.0","type":"link"}