{"product_id":"oral-bioavailability-assessment-ayman-f-el-kattan-9781118916698","title":"Oral Bioavailability Assessment: Basics and Strategies for Drug Discovery and Development","description":"Specifically geared to personnel in the pharmaceutical and biotechnology industries, this book describes the basics and challenges of oral bioavailability - one of the most significant hurdles in drug discovery and development.\u003cbr\u003e\u003cbr\u003e- Describes approaches to assess pharmacokinetics and how drug efflux and uptake transporters impact oral bioavailability\u003cbr\u003e- Helps readers reduce the failure rate of drug candidates when transitioning from the bench to the clinic during development\u003cbr\u003e- Explains how preclinical animal models - used in preclinical testing - and in vitro tools translate to humans, which is an underappreciated and complicated area of drug development\u003cbr\u003e- Includes chapters about pharmacokinetic modelling, the Biopharmaceutics Drug Disposition Classification System (BDDCS), and the Extended Clearance Classification System (ECCS)\u003cbr\u003e- Has tutorials for applying strategies to medicinal chemistry practices of drug discovery\/development\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Ayman F. El-Kattan\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 1118916697\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9781118916698\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Wiley\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 06\/06\/2017\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 448\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Hardcover\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 1.70lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 9.30h x 6.20w x 1.10d","brand":"Ayman F. El-Kattan","offers":[{"title":"Hardcover","offer_id":45933905215743,"sku":"9781118916698","price":187.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_b502a0b2-af25-42e3-af38-378e474e1d57.jpg?v=1721789879","url":"https:\/\/www.whiterainbookhouse.com\/products\/oral-bioavailability-assessment-ayman-f-el-kattan-9781118916698","provider":"WR Book House","version":"1.0","type":"link"}