{"product_id":"paediatric-formulation-nunzio-denora-9783036507408","title":"Paediatric Formulation: Design and Development","description":"\u003cp\u003eThe development of paediatric medicines can be challenging since this is a different patient population with specific needs. A medicine designed for use in paediatric patients must consider the following aspects: patient population variability; the need for dose flexibility; route of administration; patient compliance; excipient tolerability. For example, the toxicity of excipients may differ in children compared to adults and children have different taste preferences. Globally, about 75% of drugs do not carry regulatory approval for use in children; worldwide, many medications prescribed for the treatment of paediatric diseases are used off-label, and less than 20% of package inserts have sufficient information for treating children. This book provides an update on both state-of-the-art methodology and operational challenges in paediatric formulation design and development. It aims at re-evaluating what is needed for more progress in the design and development of age-appropriate treatments for paediatric diseases, focusing on: formulation development; drug delivery design; efficacy, safety, and tolerability of drugs and excipients.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Nunzio Denora\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 303650740X\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9783036507408\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Mdpi AG\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 06\/17\/2021\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 206\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Hardcover\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 1.42lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 9.61h x 6.69w x 0.69d","brand":"Nunzio Denora","offers":[{"title":"Hardcover","offer_id":47305470017791,"sku":"9783036507408","price":63.9,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_7d43340a-b3a4-46a0-ba5d-d42717d42e9d.jpg?v=1758830970","url":"https:\/\/www.whiterainbookhouse.com\/products\/paediatric-formulation-nunzio-denora-9783036507408","provider":"WR Book House","version":"1.0","type":"link"}