{"product_id":"pathobiology-of-alzheimers-disease-peter-jenner-9780122869655","title":"Pathobiology of Alzheimer's Disease","description":"\u003cb\u003eNeuroscience Perspectives\u003c\/b\u003e provides multidisciplinary reviews of topics in one of the most diverse and rapidly advancing fields in the life sciences.\u003cbr\u003eWhether you are a new recruit to neuroscience, or an established expert, look to this series for 'one-stop' sources of the historical, physiological, pharmacological, biochemical, molecular biological and therapeutic aspects of chosen research areas.\u003cbr\u003eThe last decade has seen tremendous advances in our understanding of the pathobiology of Alzheimer's disease. These will lead to the first generation of drugs aimed at prevention rather than cure. This book covers some of the most important and exciting of these advances, with chapters written by many of the leading researchers in the field.\u003cbr\u003eWith genetic studies as a backbone to this volume many chapters are devoted to the function and regulation of amyloid b-protein precursor (APP) and apolipoprotein E (ApoE). Other chapters describe cell biological approaches helping to piece together the link between the genetic alterations and the phenotype we call Alzheimer's disease.\u003cbr\u003eAlthough APP and its proteolytic cleavage product, amyloid b-protein, do not answer all the questions, detailed research into this system has undoubtedly increased our knowledge of the pathobiology of AD and has lead to the identification of other risk factors. Understanding the role of ApoE in the pathology of Alzheimer's disease promises to open a whole new field in AD research.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Peter Jenner\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 0122869656\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9780122869655\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Academic Press\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 10\/26\/1995\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 256\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Hardcover\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 1.04lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 9.22h x 6.21w x 0.76d","brand":"Peter Jenner","offers":[{"title":"Hardcover","offer_id":47135219843327,"sku":"9780122869655","price":225.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_87e08619-4604-4aeb-b07f-d95a6c2e08a8.jpg?v=1755009488","url":"https:\/\/www.whiterainbookhouse.com\/products\/pathobiology-of-alzheimers-disease-peter-jenner-9780122869655","provider":"WR Book House","version":"1.0","type":"link"}