{"product_id":"peptide-macrocycles-matthew-b-coppock-9781071616918","title":"Peptide Macrocycles: Methods and Protocols","description":"\u003cp\u003ePreface...\u003cbr\u003eTable of Contents...\u003cbr\u003eContributing Authors... \u003c\/p\u003e\u003cp\u003e\u003c\/p\u003ePart I Peptide Macrocycle Synthesis \u003cp\u003e\u003c\/p\u003e1. Three Methods for Peptide Cyclization via Lactamization\u003cbr\u003eLaura Posada and Gloria Serra \u003cp\u003e\u003c\/p\u003e2. Solid-Phase Peptide Cyclization with Two Disulfide Bridges\u003cbr\u003eDa'san M. M. Jaradat \u003cp\u003e\u003c\/p\u003e3. Peptide Macrocyclization through Palladium-Catalyzed Late-Stage C-H Activation\u003cbr\u003eChuangxu Cai, Shu Liu, and Huan Wang \u003cp\u003e\u003c\/p\u003e4. Three Methods for the Solution Phase Synthesis of Cyclic Peptides\u003cbr\u003eAngelika Ullrich, Lukas Junk, and Uli Kazmaier \u003cp\u003e\u003c\/p\u003e5. Computational Design of Structured and Functional Peptide Macrocycles\u003cbr\u003eStephanie Berger and Parisa Hosseinzadeh \u003cp\u003e\u003c\/p\u003e6. On-Resin Peptide Cyclization Using the 3-4-Amino-(Methylamino)Benzoic Acid (MeDbz) Linker\u003cbr\u003eBengt H. Gless and Christian A. Olsen \u003cp\u003e\u003c\/p\u003e7. Scalable and Efficient in planta Biosynthesis of Sunflower Trypsin Inhibitor-1 (SFTI) Peptide Therapeutics\u003cbr\u003eThomas N. G. Handley, Mark A. Jackson, and David J. Craik \u003cp\u003e\u003c\/p\u003e8. Ligation, Macrocyclization, and Simultaneous Functionalization of Peptides by Multicomponent Reactions (MCR)\u003cbr\u003eAldrin V. Vasco, Manuel G. Ricardo, Daniel G. Rivera, and Ludger A. Wessjohann \u003cp\u003e\u003c\/p\u003e9. Diels-Alder Cycloadditions for Peptide Macrocycle Formation\u003cbr\u003eJeffrey E. Montgomery and Raymond E. Moellering \u003cp\u003e\u003c\/p\u003ePart II Peptide Macrocycle Combinatorial Library Synthesis and Screening \u003cp\u003e\u003c\/p\u003e10. Protein Catalyzed Capture (PCC) Agents for Antigen Targeting\u003cbr\u003eMatthew N. Idso, Bert T. Lai, Heather D. Agnew, and James R. Heath \u003cp\u003e\u003c\/p\u003e11. Preparation of Bacterial Cell-Surface Displayed Semisynthetic Cyclic Peptides\u003cbr\u003eShubhendu Palei, Joachim Jose, and Henning D. Mootz \u003cp\u003e\u003c\/p\u003e12. The Discovery of Peptide Macrocycle Rescuers of Pathogenic Protein Misfolding and Aggregation by Integrating SICLOPPS Technology and Ultra-Throughput Screening in Bacteria\u003cbr\u003eDafni C. Delivoria and Georgios Skretas \u003cp\u003e\u003c\/p\u003e13. In Vitro Selection of Thioether-Closed Macrocycle Peptide Ligands by Means of the RaPID System\u003cbr\u003eTakayuki Katoh, Yuki Goto, and Hiroaki Suga \u003cp\u003e\u003c\/p\u003e14. MOrPH-PhD: A Phage Display System for the Functional Selection of Genetically Encoded Macrocyclic Peptides\u003cbr\u003eYu Gu, Jacob A. Iannuzzelli, and Rudi Fasan \u003cp\u003e\u003c\/p\u003e15. Discovery of Antimicrobial Peptide Macrocycles Through Bacterial Display\u003cbr\u003eJustin R. Randall, Cory D. DuPai, and Bryan W. Davies \u003cp\u003e\u003c\/p\u003ePart III Peptide Macrocycle Characterization \u003cp\u003e\u003c\/p\u003e16. Assessing the Cellular Uptake, Endosomal Escape, and Cytosolic Entry Efficiencies of Cyclic Peptides\u003cbr\u003eHeba Salim and Dehua Pei \u003cp\u003e\u003c\/p\u003e17. In silico Analysis of Peptide Macrocycle-Protein Interactions\u003cbr\u003eMargaret M. Hurley and Meagan C. Small \u003cp\u003e\u003c\/p\u003e18. Binding Characterization of Cyclic Peptide Ligands to Target Proteins and Chemical Epitopes using ELISA and Fluorescence Polarization Assays\u003cbr\u003eAriane Borges, Iryna Onasenko, and Arundhati Nag \u003cp\u003e\u003c\/p\u003e19. Determining the Binding Kinetics of Peptide Macrocycles using Bio-Layer Interferometry (BLI)\u003cbr\u003eKatherine Rhea \u003cp\u003e\u003c\/p\u003ePart IV Unique Applications of Peptide Macrocycles \u003cp\u003e\u003c\/p\u003e20. Different Approaches to Cyclize a Cell-Penetrating Peptide and to Tether Bioactive Payloads\u003cbr\u003eLucia Feni and Innes Neundorf \u003cp\u003e\u003c\/p\u003e21. Helical Stabilization of Peptide Macrocycles by Stapled Architectures\u003cbr\u003eFenfang Yang, Feng Yin, and Zigang Li \u003cp\u003e\u003c\/p\u003e22. Development and Characterization of Light Responsive Peptide Macrocycles\u003cbr\u003eLena Sobze and Ratmir Derda \u003cp\u003e\u003c\/p\u003e23. Hydrogel Formation with Enzyme-Responsive Cyclic Peptides\u003cbr\u003eAndrea S. Carlini, Mary F. Cassidy, and Nathan C. Gianneschi \u003cp\u003e\u003c\/p\u003e24. Cyclization and Self-Assembly of Cyclic Peptides\u003cbr\u003eAlejandro M駭dez-Ardoy, Ignacio Insua, Juan R. Granja, and Javier Montenegro \u003cp\u003e\u003c\/p\u003eSubject Index List...\u003cbr\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Matthew B. Coppock\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 1071616919\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9781071616918\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Humana\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 10\/02\/2022\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 469\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Paperback\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 1.83lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 10.00h x 7.00w x 0.97d","brand":"Matthew B. Coppock","offers":[{"title":"Paperback","offer_id":44069896880383,"sku":"9781071616918","price":149.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_a89cd4db-c8a6-4442-8f08-d070f44c6dac.jpg?v=1685427146","url":"https:\/\/www.whiterainbookhouse.com\/products\/peptide-macrocycles-matthew-b-coppock-9781071616918","provider":"WR Book House","version":"1.0","type":"link"}