{"product_id":"ph-deregulation-as-the-eleventh-tomas-koltai-9780443154614","title":"PH Deregulation as the Eleventh Hallmark of Cancer","description":"\u003cp\u003e\u003ci\u003epH Deregulation as the Eleventh Hallmark of Cancer\u003c\/i\u003e presents key concepts about pH deregulation in a concise and straight-forward manner. The book discusses topics such as pH regulation and metabolism, sodium hydrogen exchanger, monocarboxylate transporter, V-ATPase proton pump, carbonic anhydrases, and voltage gated sodium channels. In addition, it covers clinical and therapeutic implications and future perspectives. This is a valuable resource for researchers, oncologists, students and members of the biomedical and medical fields who want to learn more about the role of pH deregulation in cancer treatment.\u003c\/p\u003e \u003cp\u003epH deregulation can improve the outcome of classical treatments without adding toxicity to them, and the book shows that treating the pH peculiarities of cancer is simple and can be performed with existing drugs. Based on the classification of tumor malignancy in ten hallmarks, the authors put pH deregulation at the spotlight and separated from metabolic reprogramming due to its impact on all other hallmarks, proposing it as an additional characteristic to evaluate and fight cancer.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Tomas Koltai, Larry Fliegel, Stephan J. Reshkin\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 0443154619\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9780443154614\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Academic Press\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 06\/30\/2023\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 190\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Paperback","brand":"Tomas Koltai","offers":[{"title":"Paperback","offer_id":45897328099583,"sku":"9780443154614","price":150.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_db92c879-4190-4355-9307-11b019a089a2.jpg?v=1721373679","url":"https:\/\/www.whiterainbookhouse.com\/products\/ph-deregulation-as-the-eleventh-tomas-koltai-9780443154614","provider":"WR Book House","version":"1.0","type":"link"}