{"product_id":"photomodulation-of-supramolecular-systems-containing-johannes-karcher-9783832550998","title":"Photomodulation of Supramolecular Systems Containing Bioactive Small Molecules and Biopolymers","description":"Molecular photoswitches can change their conformation upon irradiation with light and convert this molecular movement into macroscopic changes of sophisticated materials. By combining state-of-the-art azobenzenes with supramolecular low-molecular-weight gelators, based on cyclic dipeptides, photomodulation of hydrogels was achieved. Photochromic amino acids with structures related to the natural L-phenylalanine were an essential element. The supramolecular hydrogels are multi-responsive towards pH, ions, temperature, and, in particular, light. Hereby the gelator F\u003csub\u003e2\u003c\/sub\u003e-PAP-DKP-Lys can be turned into a sol upon irradiation with green light and within this transition a drug, for example an antibiotic, was released. The further improved supergelator Cl\u003csub\u003e4\u003c\/sub\u003e-PAP-DKP-Lys\u003csub\u003e2\u003c\/sub\u003e is reversibly switchable with red and violet light in the range of 0.2-0.5 % in an isotonic Ringer's solution. At a concentration of 1 %, the hydrogel consisting of Cl\u003csub\u003e4\u003c\/sub\u003e-PAP-DKP-Lys\u003csub\u003e2\u003c\/sub\u003e remains stable in a boiling water bath. Thus, we envision that the enhanced stability of the supramolecular assembly of Cl\u003csub\u003e4\u003c\/sub\u003e-PAP-DKP-Lys\u003csub\u003e2\u003c\/sub\u003e and orthogonal biocompatibility of F\u003csub\u003e2\u003c\/sub\u003e-PAP-DKP-Lys, could enable further applications, spanning from regenerative medicine to electronic devices, besides our future vision towards photopharmacology.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Johannes Karcher\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 3832550992\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9783832550998\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Logos Verlag Berlin\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 04\/06\/2020\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 322\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Paperback","brand":"Johannes Karcher","offers":[{"title":"Paperback","offer_id":48450140700927,"sku":"9783832550998","price":94.0,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_78e2f3f7-9f7a-4730-88ca-5427c671a75f.jpg?v=1777266386","url":"https:\/\/www.whiterainbookhouse.com\/products\/photomodulation-of-supramolecular-systems-containing-johannes-karcher-9783832550998","provider":"WR Book House","version":"1.0","type":"link"}