{"product_id":"phylogenetic-analysis-of-viral-quasispecies-patricia-buendia-9783836434584","title":"Phylogenetic Analysis of Viral Quasispecies","description":"A new approach in the analysis of viral evolution is presented in this book, an approach that merges Phylogenetic analysis and Bioinformatic techniques. Patterns of viral evolution are inferred from serially-sampled sequence data, i.e., sequence data obtained from strains isolated at consecutive time points from a single patient or host. Traditional phylogenetic methods assume a tree-like evolutionary model, while many RNA viruses have the capacity to exchange genetic material with one another using a process called re-combination. A genealogy involving recombination is best described by a net-work structure. A more general approach was implemented in a new compu-tational tool, Sliding MinPD, one that is mindful of the sampling times of the input sequences and that reconstructs the viral evolutionary relationships in the form of a network structure with implicit representations of recombi-nation events. The underlying network organization reveals unique patterns of viral evolution and could help explain the emergence of disease-associated mutants and drug-resistant strains, with implications for patient prognosis and treatment strategies.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Patricia Buendia\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 383643458X\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9783836434584\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e VDM Verlag Dr. Mueller E.K.\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 01\/07\/2008\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 212\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Paperback\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 0.76lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 9.61h x 6.69w x 0.45d","brand":"Patricia Buendia","offers":[{"title":"Paperback","offer_id":47760078536959,"sku":"9783836434584","price":85.32,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_4a1d044f-2e80-4162-9db0-8c286fa6ec4b.jpg?v=1765513242","url":"https:\/\/www.whiterainbookhouse.com\/products\/phylogenetic-analysis-of-viral-quasispecies-patricia-buendia-9783836434584","provider":"WR Book House","version":"1.0","type":"link"}