{"product_id":"planning-and-analyzing-clinical-trials-geraldine-rauch-9783319737690","title":"Planning and Analyzing Clinical Trials with Composite Endpoints","description":"Preface.- Contents.- Part I General Introduction to Composite Endpoints.- 1 Definition and Rationale.- 2 Challenges of Composite Endpoints.- 3 Guideline View - Recommendations and Requirements.- 4 Clinical Trial Examples.- Part II Confirmatory Test Problem for a Single (Composite) Endpoint.- 5 The Single-Stage Design.- 6 Group-Sequential and Adaptive Designs.- 7 Related Software Code.- Part III Confirmatory Multiple Test Problem.- 8 Correlation Between Test Statistics.- 9 The Single-Stage Design.- 10 Group-Sequential and Adaptive Designs.- 11 Related Software Code.- Part IV Confirmatory Test Problem for a Weighted Composite Endpoint.- 12 Weighted Binary Composite Endpoint.- Weighted Time-to-Event Composite Endpoint.- 14 OtherWeighted Effect Measures.- 15 Related Software Code.- Part V Descriptive and Confirmatory Evaluation of the Components.- 16 Descriptive Analysis of the Components.- 17 Supplementary Confirmatory Analyses of the Components.- 18 Related Software Code.- Part VI Illustrating Clinical Trial Examples.- 19 Clinical Trial Examples with Binary (Composite) Endpoints.- 20 Clinical Trial Examples with (Composite) Time-to-Event Endpoints.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Geraldine Rauch, Svenja Schüler, Meinhard Kieser\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 3319737694\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9783319737690\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Springer\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 05\/31\/2018\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 255\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Hardcover\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 1.23lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 9.21h x 6.14w x 0.63d","brand":"Geraldine Rauch","offers":[{"title":"Hardcover","offer_id":44073595437311,"sku":"9783319737690","price":159.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_534d0f5f-a4ac-4065-860b-2adc96ecb283.jpg?v=1685448754","url":"https:\/\/www.whiterainbookhouse.com\/products\/planning-and-analyzing-clinical-trials-geraldine-rauch-9783319737690","provider":"WR Book House","version":"1.0","type":"link"}