{"product_id":"protein-folding-and-metal-ions-clzaudio-m-gomes-9781439809648","title":"Protein Folding and Metal Ions: Mechanisms, Biology and Disease","description":"\u003cp\u003eThe role of metal ions in protein folding and structure is a critical topic to a range of scientists in numerous fields, particularly those working in structural biology and bioinorganic chemistry, those studying protein folding and disease, and those involved in the molecular and cellular aspects of metals in biological systems. \u003cstrong\u003eProtein Folding and Metal Ions: Mechanisms, Biology and Disease\u003c\/strong\u003e presents the contributions of a cadre of international experts who offer a comprehensive exploration of this timely subject at the forefront of current research.\u003c\/p\u003e\u003cp\u003eDivided into four sections, this volume: \u003c\/p\u003e\u003cul\u003e \u003cp\u003e \u003c\/p\u003e \u003cli\u003eProvides case study examples of protein folding and stability studies in particular systems or proteins that comprise different metal ions of co-factors\u003c\/li\u003e \u003cli\u003eReviews the proteins that shuttle metal ions in the cell to a particular target metalloprotein\u003c\/li\u003e \u003cli\u003eIllustrates how metal binding can be connected to pathological protein conformations in unrelated diseases, from cancer to protein deposition disorders such as Parkinson's disease\u003c\/li\u003e \u003cli\u003eAddresses protein redesign of metal-containing proteins by computational methods, folding simulation studies, and work on model peptides -- dissecting the relative energetic contribution of metals sites to protein folding and stability\u003c\/li\u003e \u003c\/ul\u003e\u003cp\u003eTogether, the 13 chapters in this text cogently describe the state of the science today, illuminate current challenges, propose future possibilities, and encourage further study in this area that offers much promise especially with regard to novel approaches to the treatment of some of the most challenging and tragic diseases.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Cláudio M. Gomes\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 143980964X\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9781439809648\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e CRC Press\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 10\/05\/2010\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 308\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Hardcover\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 1.35lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 9.21h x 6.14w x 0.75d\u003cbr\u003e\u003cbr\u003e\u003cb\u003eReview Citation(s): \u003c\/b\u003e\u003cbr\u003e\u003ci\u003eReference and Research Bk News\u003c\/i\u003e 04\/01\/2011 pg. 308","brand":"Cláudio M. Gomes","offers":[{"title":"Hardcover","offer_id":48088264048895,"sku":"9781439809648","price":250.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_7ef9ee03-57a2-4a9b-aa1b-c277e3b3b8f7.jpg?v=1769103947","url":"https:\/\/www.whiterainbookhouse.com\/products\/protein-folding-and-metal-ions-clzaudio-m-gomes-9781439809648","provider":"WR Book House","version":"1.0","type":"link"}