{"product_id":"ras-family-gtpases-channing-der-9781402043284","title":"Ras Family Gtpases","description":"\u003cp\u003eSince 1982, Ras proteins have been the subject of intense research investigation by the biomedical research community. The wide interest in Ras has been stimulated for three key reasons.\u003c\/p\u003e \u003cp\u003eFirst, their frequent mutational activation in human cancers establishes Ras proteins as important mediators of oncogenesis and targets for anti-cancer drug discovery. Second, Ras proteins act as signalling nodes activated by diverse extracellular stimuli, and activated Ras in turn regulates a diversity of cytoplasmic signalling networks. Third, Ras proteins are founding members of a large superfamily of Ras-related small GTPases. Over 150 Ras-related small GTPases are found in the human genome, with orthologs found in all vertebrate species and invertebrates.\u003c\/p\u003e \u003cp\u003eThis book features chapters by leading investigators in the field that highlight the current state-of-the art in Ras biochemistry, structure and biology. This book is an excellent reference for students in the biomedical sciences and for investigators in the field.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Channing Der\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 1402043287\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9781402043284\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Springer\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 09\/13\/2006\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 397\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Hardcover\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 1.88lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 9.46h x 6.56w x 0.85d","brand":"Channing Der","offers":[{"title":"Hardcover","offer_id":44064557334783,"sku":"9781402043284","price":249.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_9d26f6f4-348f-47ab-aeea-057a7e611c94.jpg?v=1685396189","url":"https:\/\/www.whiterainbookhouse.com\/products\/ras-family-gtpases-channing-der-9781402043284","provider":"WR Book House","version":"1.0","type":"link"}