{"product_id":"receptor-based-drug-design-paul-leff-9780824701628","title":"Receptor - Based Drug Design","description":"\u003cp\u003eEmploying a wide range of examples from G-protein-coupled receptors and ligand-gated ion channels, this detailed, single-source reference illustrates the principles of pharmacological analysis and receptor classification that are the basis of rational drug design. \u003cbr\u003eExplains the experimental and theoretical methods used to characterize interactions between ligands and receptors-providing the pharmacological information needed to solve treatment problems and facilitate the drug design process! \u003cbr\u003eDemonstrating the achievements of the receptor-based approach in therapeutics and indicating future directions, Receptor-Based Drug Design\u003c\/p\u003e\u003cli\u003eintroduces novel computer-assisted strategies for the design of new agonists, antagonists, and inverse agonists for G-protein-coupled receptors \u003cbr\u003e \u003c\/li\u003e\u003cli\u003eshows how to assess agonist concentration-effect curve data \u003cbr\u003e \u003c\/li\u003e\u003cli\u003ediscusses radioligand binding assays \u003cbr\u003e \u003c\/li\u003e\u003cli\u003epresents new in vitro multiarray assays for G-protein-coupled receptors \u003cbr\u003e \u003c\/li\u003e\u003cli\u003eexplains the use of individual second messenger signaling responses in analyzing drug-receptor interactions \u003cbr\u003e \u003c\/li\u003e\u003cli\u003eexamines the role of electrophysiology in finding new drugs and drug targets \u003cbr\u003e \u003c\/li\u003e\u003cli\u003edescribes selectively acting b-adrenoceptor agonists and glucocorticoid steroids for asthma treatment \u003cbr\u003e \u003c\/li\u003e\u003cli\u003eoutlines the rationale for using angiotensin receptor antagonists \u003cbr\u003e \u003c\/li\u003e\u003cli\u003eand more! \u003cbr\u003eWritten by over 25 international authorities and containing nearly 1200 bibliographic citations, Receptor-Based Drug Design is a practical resource for pharmacologists, pharmacists, and pharmaceutical scientists; organic and medicinal chemists and biochemists; molecular biologists; biomedical researchers; and upper-level undergraduate and graduate students in these disciplines.\u003c\/li\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Paul Leff\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 0824701623\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9780824701628\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e CRC Press\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 04\/10\/1998\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 400\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Hardcover\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 1.66lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 9.30h x 6.38w x 1.25d","brand":"Paul Leff","offers":[{"title":"Hardcover","offer_id":48086983147775,"sku":"9780824701628","price":230.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_f0453cda-5376-4b95-8e39-27a113872c95.jpg?v=1769097628","url":"https:\/\/www.whiterainbookhouse.com\/products\/receptor-based-drug-design-paul-leff-9780824701628","provider":"WR Book House","version":"1.0","type":"link"}