{"product_id":"recombinant-technology-in-hemostasis-and-leon-w-hoyer-9780306438936","title":"Recombinant Technology in Hemostasis and Thrombosis","description":"Characterization of Gene and Protein Structure.- Biosynthesis and Assembly of the Factor VIII-von Willebrand Factor Complex.- Factor IX: Gene Structure and Protein Synthesis.- Antithrombin III Genetics, Structure and Function.- Interactions Between the Functional Domains of Antithrombin III.- Protein C: Gene Structure and Protein Synthesis.- Structural and Functional Properties of Protein C.- Molecular Defects Affecting Hemostasis.- Molecular Defects in Hemophilia A.- Molecular Defects in Hemophilia B.- Molecular Defects in Human Antithrombin III Deficiency.- The Biologic Impact of Hereditary Defects that Cause Thrombosis.- Protein Production by Recombinant Technology.- Factors Limiting Expression of Secreted Proteins in Mammalian Cells.- Synthesis of Biologically Active Vitamin K-Dependent Coagulation Factors.- The Expression of Therapeutic Proteins in Transgenic Animals.- Clinical use of Proteins Produced by Recombinant Technology.- The Use of Animal Models to Evaluate Proteins Produced by Recombinant Technology.- Experiences with Recombinant Factor VIIa in Hemophiliacs.- Clinical Trials of Factor VIII Produced by Recombinant Technology.- Clinical Trials of Recombinant Factor VIII.- Concluding Overview.- The Impact of Recombinant Technologies in Understanding Plasma Proteins Important for Hemostasis and Thrombosis.- Contributors.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Leon W. Hoyer,Leon Ed Hoyer,William Drohan\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 0306438933\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9780306438936\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Springer\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 05\/31\/1991\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 272\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Hardcover\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 1.52lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 10.00h x 7.00w x 0.63d","brand":"Leon W. Hoyer","offers":[{"title":"Hardcover","offer_id":47420893659391,"sku":"9780306438936","price":99.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_5d762eaa-6f92-41c8-a5e3-e3306e067a14.jpg?v=1761526455","url":"https:\/\/www.whiterainbookhouse.com\/products\/recombinant-technology-in-hemostasis-and-leon-w-hoyer-9780306438936","provider":"WR Book House","version":"1.0","type":"link"}