{"product_id":"ribosome-biogenesis-karl-dieter-entian-9781071625002","title":"Ribosome Biogenesis: Methods and Protocols","description":"This Open Access volume provides comprehensive reviews and describes the latest techniques to study eukaryotic ribosome biogenesis. For more than 50 years ribosomes are a major research topic. Our knowledge about ribosome biogenesis and function such as transcription, mRNA modification, and translation was the sine qua non for developing the powerful RNA-based vaccines against RNA-viruses causing the world-threatening Covid-19 pandemia. The chapters in this book are organized into six parts. Part One discusses a comparative survey about the unity and diversity of ribosome biogenesis in pro- and eukaryotic cells. Part Two deals with the genomic organization of eukaryotic rDNA and the role of RNA polymerase I in ribosomal RNA transcription. Part Three explores in vitro methods to study RNA polymerase I structure and its function, and Part Four analyzes the nucleo-cytoplasmic transport of assembled ribosomes and RNP complexes. Part Five covers modifications that increasethe complexity of rRNAs, and Part Six provides readers with a review of eukaryotic translation and - for the first time - describes a new method to analyze translation in vitro. Written in the highly successful \u003ci\u003eMethods in Molecular Biology\u003c\/i\u003e series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. \u003cbr\u003eCutting-edge and comprehensive, \u003ci\u003eRibosome Biogenesis: Methods and Protocols\u003c\/i\u003e is a valuable resource for scientists and researchers interested in learning more about the increasing importance of in vitro RNA-technologies. \u003cp\u003e\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Karl-Dieter Entian\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 1071625004\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9781071625002\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Humana\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 07\/08\/2022\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 287\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Hardcover\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 1.64lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 10.00h x 7.00w x 0.69d","brand":"Karl-Dieter Entian","offers":[{"title":"Hardcover","offer_id":44076244336895,"sku":"9781071625002","price":59.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_9ed9866b-e7cf-4f07-b4bb-16e7d8513d2d.jpg?v=1685463941","url":"https:\/\/www.whiterainbookhouse.com\/products\/ribosome-biogenesis-karl-dieter-entian-9781071625002","provider":"WR Book House","version":"1.0","type":"link"}