{"product_id":"role-of-capsaicin-in-oxidative-sanjay-k-srivastava-9789400763166","title":"Role of Capsaicin in Oxidative Stress and Cancer Diet \u0026 Cancer 3","description":"This book describes the mechanism of the anti-cancer effects of capsaicin including the involvement of cytochrome P-450 in the bioactivation; identification of mitochondria as the key target site for oxidative stress; involvement of mitochondrial respiratory chain in the production of ROS; prevention of chemically-induced carcinogenesis, discussion on TRPV-1 receptor mediated or independent anti-cancer effects; identification of p53 activation as a possible mechanism; involvement of Cox-2 in apoptosis, suppression of transcription factors such as NF-kB and STAT-3; inhibition of cell survival pathways including PI3K\/Akt and the involvement of intrinsic mitochondrial cell death pathway.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Sanjay K. Srivastava\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 9400763166\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9789400763166\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Springer\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 05\/07\/2013\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 178\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Hardcover\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 0.95lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 9.20h x 6.00w x 0.50d","brand":"Sanjay K. Srivastava","offers":[{"title":"Hardcover","offer_id":44652427968767,"sku":"9789400763166","price":109.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_da0444dd-f5f5-45a5-8860-b7e0a5c3a19a.jpg?v=1704216046","url":"https:\/\/www.whiterainbookhouse.com\/products\/role-of-capsaicin-in-oxidative-sanjay-k-srivastava-9789400763166","provider":"WR Book House","version":"1.0","type":"link"}