{"product_id":"salmonella-steffen-porwollik-9781904455738","title":"Salmonella: From Genome to Function","description":"\u003cp\u003eSalmonellae are important pathogens, responsible for an estimated one million deaths and 100 million human infections annually. Their genomes are mosaic puzzles - results of lateral transfer events that occur within a stable genetic background. Extraordinary diversity of host ranges and pathogenicity traits between different strains are the consequence of both specific genome insertions\/deletions and minute changes in genome composition. Genomic information decoded from a multitude of different \u003cem\u003eSalmonella\u003c\/em\u003e strains and new dramatic insights into pathogenic processes emphasize the fact that \u003cem\u003eSalmonella\u003c\/em\u003eresearch is currently at a very exciting juncture. In addition to their fascinating resilience in both the environment and eukaryotic hosts, \u003cem\u003eSalmonella\u003c\/em\u003e prefers tumours over any other location within the human host (by a factor of 1000 or more). This ability could propel \u003cem\u003eSalmonella\u003c\/em\u003e into future use as a therapeutic delivery agent to control and\/or cure cancers. In this book, internationally acclaimed experts review cutting-edge topics in \u003cem\u003eSalmonella\u003c\/em\u003e genomics and molecular biology, providing a timely snapshot of the current state of research. Topics include latest approaches to sub-species level classification and phage typing of \u003cem\u003eSalmonella\u003c\/em\u003e, comparative genomics, the search for genetic determinants for survival of the bacterium in different environments and the evolution of niche specialization by \u003cem\u003eSalmonella\u003c\/em\u003e. The book also explores the latest genomic information and molecular characterizations of sRNAs and complements of fimbriae, flagella and secreted virulence factors. Moreover, \u003cem\u003eS.\u003c\/em\u003e Typhi pathogenesis, interactions of the host with intracellular \u003cem\u003eSalmonella\u003c\/em\u003e and the host's anti-\u003cem\u003eSalmonella\u003c\/em\u003e immune response are reviewed. The current knowledge on \u003cem\u003eSalmonella\u003c\/em\u003e biofilm formation and a progress report on using \u003cem\u003eSalmonella\u003c\/em\u003e as an anti-tumour tool conclude this compendium. Essential reading for all researchers working with \u003cem\u003eSalmonella\u003c\/em\u003e and related organisms, and recommended reading for other scientists working on bacterial genomics, molecular biology and bacterial molecular and cellular pathogenesis.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Steffen Porwollik\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 1904455735\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9781904455738\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Caister Academic Press Limited\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 01\/01\/2011\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 314\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Hardcover\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 1.89lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 9.80h x 7.00w x 0.80d\u003cbr\u003e\u003cbr\u003e\u003cb\u003eReview Citation(s): \u003c\/b\u003e\u003cbr\u003e\u003ci\u003eReference and Research Bk News\u003c\/i\u003e 04\/01\/2011 pg. 308","brand":"Steffen Porwollik","offers":[{"title":"Hardcover","offer_id":48445837672703,"sku":"9781904455738","price":250.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_08c66803-f6a8-4aa4-8cf2-cb8c0d33122c.jpg?v=1777220989","url":"https:\/\/www.whiterainbookhouse.com\/products\/salmonella-steffen-porwollik-9781904455738","provider":"WR Book House","version":"1.0","type":"link"}