{"product_id":"sample-size-calculations-for-clustered-chul-ahn-9780367575991","title":"Sample Size Calculations for Clustered and Longitudinal Outcomes in Clinical Research","description":"\u003cp\u003eAccurate sample size calculation ensures that clinical studies have adequate power to detect clinically meaningful effects. This results in the efficient use of resources and avoids exposing a disproportionate number of patients to experimental treatments caused by an overpowered study. \u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cp\u003e\u003cstrong\u003eSample Size Calculations for Clustered and Longitudinal Outcomes in Clinical Research\u003c\/strong\u003e explains how to determine sample size for studies with correlated outcomes, which are widely implemented in medical, epidemiological, and behavioral studies.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cp\u003e\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cp\u003eThe book focuses on issues specific to the two types of correlated outcomes: longitudinal and clustered. For clustered studies, the authors provide sample size formulas that accommodate variable cluster sizes and within-cluster correlation. For longitudinal studies, they present sample size formulas to account for within-subject correlation among repeated measurements and various missing data patterns. For multiple levels of clustering, the level at which to perform randomization actually becomes a design parameter. The authors show how this can greatly impact trial administration, analysis, and sample size requirement.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cp\u003e\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cp\u003eAddressing the overarching theme of sample size determination for correlated outcomes, this book provides a useful resource for biostatisticians, clinical investigators, epidemiologists, and social scientists whose research involves trials with correlated outcomes. Each chapter is self-contained so readers can explore topics relevant to their research projects without having to refer to other chapters.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Chul Ahn, Moonseoung Heo, Song Zhang\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 036757599X\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9780367575991\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e CRC Press\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 06\/30\/2020\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 260\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Paperback\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 0.82lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 9.21h x 6.14w x 0.55d","brand":"Chul Ahn","offers":[{"title":"Paperback","offer_id":43943335002367,"sku":"9780367575991","price":59.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/products\/img_6e309e1a-d4d0-47d1-9f96-6948db11c6a3.jpg?v=1681497536","url":"https:\/\/www.whiterainbookhouse.com\/products\/sample-size-calculations-for-clustered-chul-ahn-9780367575991","provider":"WR Book House","version":"1.0","type":"link"}