{"product_id":"sample-size-calculations-in-clinical-shein-chung-chow-9781138740983","title":"Sample Size Calculations in Clinical Research","description":"\u003cp\u003ePraise for the Second Edition: \u003c\/p\u003e\u003cp\u003e\"... this is a useful, comprehensive compendium of almost every possible sample size formula. The strong organization and carefully defined formulae will aid any researcher designing a study.\" -\u003cb\u003e\u003ci\u003eBiometrics\u003c\/i\u003e\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003e\"\u003ci\u003eThis impressive book contains formulae for computing sample size in a wide range of settings. One-sample studies and two-sample comparisons for quantitative, binary, and time-to-event outcomes are covered comprehensively, with separate sample size formulae for testing equality, non-inferiority, and equivalence. Many less familiar topics are also covered ...\u003c\/i\u003e\" - \u003cb\u003e\u003ci\u003eJournal of the Royal Statistical Society\u003c\/i\u003e\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSample Size Calculations in Clinical Research, Third Edition\u003c\/b\u003e presents statistical procedures for performing sample size calculations during various phases of clinical research and development. A comprehensive and unified presentation of statistical concepts and practical applications, this book includes a well-balanced summary of current and emerging clinical issues, regulatory requirements, and recently developed statistical methodologies for sample size calculation.\u003c\/p\u003e\u003cp\u003eFeatures: \u003c\/p\u003e\u003cul\u003e \u003cp\u003e \u003c\/p\u003e \u003cli\u003eCompares the relative merits and disadvantages of statistical methods for sample size calculations\u003c\/li\u003e \u003cp\u003e \u003c\/p\u003e \u003cli\u003eExplains how the formulae and procedures for sample size calculations can be used in a variety of clinical research and development stages\u003c\/li\u003e \u003cp\u003e \u003c\/p\u003e \u003cli\u003ePresents real-world examples from several therapeutic areas, including cardiovascular medicine, the central nervous system, anti-infective medicine, oncology, and women's health\u003c\/li\u003e \u003cp\u003e \u003c\/p\u003e \u003cli\u003eProvides sample size calculations for dose response studies, microarray studies, and Bayesian approaches\u003c\/li\u003e \u003c\/ul\u003e\u003cp\u003eThis new edition is updated throughout, includes many new sections, and five new chapters on emerging topics: two stage seamless adaptive designs, cluster randomized trial design, zero-inflated Poisson distribution, clinical trials with extremely low incidence rates, and clinical trial simulation.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Shein-Chung Chow, Jun Shao, Hansheng Wang\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 1138740985\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9781138740983\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e CRC Press\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 08\/30\/2017\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 510\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Hardcover\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 2.50lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 10.10h x 7.00w x 1.30d","brand":"Shein-Chung Chow","offers":[{"title":"Hardcover","offer_id":43924210450687,"sku":"9781138740983","price":170.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/products\/img_cde5c048-bdad-49ab-afb1-c7cb0c8b20f4.jpg?v=1681069127","url":"https:\/\/www.whiterainbookhouse.com\/products\/sample-size-calculations-in-clinical-shein-chung-chow-9781138740983","provider":"WR Book House","version":"1.0","type":"link"}