{"product_id":"sarcopenia-age-related-muscle-wasting-gordon-s-lynch-9789400790445","title":"Sarcopenia - Age-Related Muscle Wasting and Weakness: Mechanisms and Treatments","description":"1.Overview.- 2. Molecular mechanisms of muscle wasting in cancer and ageing: cachexia versus sarcopenia.- 3. Age-related remodeling of neuromuscular junctions.- 4.Motor unit remodeling during aging.- 5. Age-related decline in actomyosin structure and function.- 6. Excitation-contraction coupling in aged skeletal muscle.- 7. Mitochondrial function in aging skeletal muscle.- 8. Fibrosis and skeletal muscle aging.- 9. Nuclear apoptosis and sarcopenia.- 10. Age-related changes in the molecular regulation of skeletal muscle mass.- 11. Genetic variation and skeletal muscle traits: implications for sarcopenia.- 12. Proteomic profiling of aged skeletal muscle.- 13. Aging, exercise and muscle protein metabolism.- 14. Reactive oxygen species generation and skeletal muscle wasting - implications for sarcopenia.- 15. Exercise as a countermeasure for sarcopenia.- 16. Role of contraction-induced injury in age-related muscle wasting and weakness.- 17. Role of IGF-I signaling in age-related changes in skeletal muscle.- 18. Role of myostatin and TGF-beta signaling in skeletal muscle growth and development: implications for sarcopenia.- 19. β-Adrenergic signaling in sarcopenia and other muscle wasting disorders.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Gordon S. Lynch\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 9400790449\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9789400790445\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Springer\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 11\/12\/2014\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 479\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Paperback\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 1.52lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 9.21h x 6.14w x 1.00d","brand":"Gordon S. Lynch","offers":[{"title":"Paperback","offer_id":45478835781887,"sku":"9789400790445","price":219.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_7f18d874-ffa5-43bf-8ed0-b958e5df8513.jpg?v=1715935822","url":"https:\/\/www.whiterainbookhouse.com\/products\/sarcopenia-age-related-muscle-wasting-gordon-s-lynch-9789400790445","provider":"WR Book House","version":"1.0","type":"link"}