{"product_id":"schistosomes-liver-flukes-and-helicobacter-the-international-agency-for-research-on-9789283212614","title":"Schistosomes, Liver Flukes and Helicobacter Pylori","description":"Evaluates the carcinogenic risk to humans posed by infection with three schistosoma trematodes, three liver flukes and the bacterium \u003ci\u003eHelicobacter pylori\u003c\/i\u003e. These biological agents were selected for evaluation on the basis of evidence suggesting a causal association between infection and the development of human cancers. \u003cbr\u003e\u003cbr\u003eThe first monograph assesses data on \u003ci\u003eSchistosoma haematobium S. mansoni\u003c\/i\u003e and \u003ci\u003eS. japonicum\u003c\/i\u003e, the three species which account for the vast majority of schistosomal disease in humans. The most extensive sections evaluate the results of studies of cancer in humans and experimental animals, concentrating on the strength of evidence linking infection with \u003ci\u003eS. haematobium \u003c\/i\u003eto squamous-cell carcinoma of the urinary bladder, and infection with \u003ci\u003eS. mansoni \u003c\/i\u003eor \u003ci\u003eS. japonicum \u003c\/i\u003eto an increased risk for cancers of the gastrointestinal tract. The monograph concludes that infection with \u003ci\u003eS. haematobium \u003c\/i\u003eis carcinogenic to humans and that infection with \u003ci\u003eS. japonicum \u003c\/i\u003eis possibly carcinogenic to humans; infection with \u003ci\u003eS. mansoni \u003c\/i\u003ecould not be classified. \u003cbr\u003e\u003cbr\u003eThe second monograph on liver flukes evaluates data on \u003ci\u003eOpisthorchis viverrini\u003c\/i\u003e \u003ci\u003eO. felineus \u003c\/i\u003eand \u003ci\u003eClonorchis sinensis\u003c\/i\u003e. These foodborne trematodes establish a chronic infection of the bile ducts and more rarely the pancreatic duct and gall-bladder of humans and other mammals. Most carcinogenicity data centre on the possibility that these trematodes are involved in the development of cholangiocarcinoma or liver cancer. The monograph concludes that infection with O\u003ci\u003e. viverrini \u003c\/i\u003eis carcinogenic to humans and that infection with \u003ci\u003eC. sinensis \u003c\/i\u003eis probably carcinogenic to humans; infection with \u003ci\u003eO. felineus \u003c\/i\u003ecould not be classified. \u003cbr\u003e\u003cbr\u003eThe final monograph evaluates data on \u003ci\u003eHelicobacter pylori\u003c\/i\u003e. More than half of the world's population may be infected with this bacterium, which is responsible for most cases of chronic gastritis and duodenal ulcer. Citing several studies linking infection to gastric cancer in humans, the monograph concludes that infection with \u003ci\u003eH. pylori \u003c\/i\u003eis carcinogenic to humans.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e The International Agency for Research on\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 9283212614\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9789283212614\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e World Health Organization\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 11\/01\/1994\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 270\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Paperback\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 1.05lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 9.40h x 6.80w x 0.60d","brand":"The International Agency for Research on","offers":[{"title":"Paperback","offer_id":48450181497087,"sku":"9789283212614","price":66.0,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_ccca8d9f-b8eb-492b-b8ce-c6bc0074e491.jpg?v=1777266554","url":"https:\/\/www.whiterainbookhouse.com\/products\/schistosomes-liver-flukes-and-helicobacter-the-international-agency-for-research-on-9789283212614","provider":"WR Book House","version":"1.0","type":"link"}