{"product_id":"simvastatin-solid-dispersion-prepared-by-chaudhary-haresh-9783846504055","title":"Simvastatin Solid Dispersion Prepared by Microwave Fusion Technique","description":"Simvastatin, a crystalline substance, is a widely used drug for the treatment of hypercholesterolemia. It is a BCS class II drug, having low aqueous solubility (0.76 mg\/L) exhibiting poor dissolution pattern and low oral bioavailability (5%). The purpose of this study was to apply the attractive technique of the microwaves fusion for the preparation of solvent-Simvastatin, a crystalline substance, is a widely used drug for the treatment of hypercholesterolemia. It is a BCS class II drug, having low aqueous solubility (0.76 mg\/L) exhibiting poor dissolution pattern and low oral bioavailability (5%). The purpose of this study was to apply the attractive technique of the microwaves fusion for the preparation of solvent-free solid dispersions and to enhance the solubility and dissolution rate of simvastatin by a solid dispersion.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Chaudhary Haresh, Patel B. N., Patel D. M.\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 384650405X\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9783846504055\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e LAP Lambert Academic Publishing\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 02\/13\/2014\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 124\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Paperback\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 0.42lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 9.00h x 6.00w x 0.29d","brand":"Chaudhary Haresh","offers":[{"title":"Paperback","offer_id":44079451832575,"sku":"9783846504055","price":59.29,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_0992bbf9-7fa6-4c90-b157-c57d55abe420.jpg?v=1685481221","url":"https:\/\/www.whiterainbookhouse.com\/products\/simvastatin-solid-dispersion-prepared-by-chaudhary-haresh-9783846504055","provider":"WR Book House","version":"1.0","type":"link"}