{"product_id":"sirtuin-biology-in-endocrinology-and-shay-welch-9798887404554","title":"Sirtuin Biology in Endocrinology and Metabolic Disease","description":"Sirtuins refer to a class of signaling proteins involved in metabolic regulation. They are members of the class III family of NAD-dependent histone deacetylases (HDAC). They are involved in a variety of physiological processes ranging from metabolism and endocrine function control to immune coordination and cellular responses to stress. Sirtuin-1 (SIRT1) plays an important role in epigenetics, immunology, and endocrinology. SIRT1's diverse roles include energy sensing metabolic homeostasis regulation, and deacetylation of histone and non-histone proteins in numerous tissues. It also facilitates neuro-endocrine regulation through hypothalamus-pituitary axis stimulation, and synthesis and maintenance of reproductive hormones via steroidogenesis. Some of the other functions involve maintenance of innate and adaptive immune systems via T and B cell maturation regulation, chronic inflammation, and autoimmune diseases. This book provides significant information of sirtuin biology as well as its importance in endocrinology and metabolic disease. It will provide comprehensive knowledge to the readers.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Shay Welch\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 8887404550\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9798887404554\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e American Medical Publishers\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 09\/26\/2023\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 248\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Hardcover\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 1.92lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 11.00h x 8.50w x 0.63d","brand":"Shay Welch","offers":[{"title":"Hardcover","offer_id":44254784094463,"sku":"9798887404554","price":154.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_6157ba1e-713d-4201-8fba-28f3d508d277.jpg?v=1694614345","url":"https:\/\/www.whiterainbookhouse.com\/products\/sirtuin-biology-in-endocrinology-and-shay-welch-9798887404554","provider":"WR Book House","version":"1.0","type":"link"}