{"product_id":"statistical-mechanics-and-stability-of-earl-prohofsky-9780521451840","title":"Statistical Mechanics and Stability of Macromolecules","description":"This book develops a statistical mechanical analysis of the stability of biological macromolecules. The author's approach is valid both for the long time-scale needed for DNA bond disruption, and also for highly cooperative transitions needed to explain helix melting. Prohofsky develops a new theoretical approach for executing macromolecule calculations. In particular the author devises a method for describing chemical bond disruption in these large systems, which is then used to determine when the helix melts and how drugs can dissociate from the helix. The author finds melting temperatures to be in excellent agreement with experimental observations.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Earl Prohofsky\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 0521451841\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9780521451840\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Cambridge University Press\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 07\/28\/1995\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 240\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Hardcover\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 1.00lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 9.26h x 6.25w x 0.80d","brand":"Earl Prohofsky","offers":[{"title":"Hardcover","offer_id":47422173774079,"sku":"9780521451840","price":170.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_76f11a38-97de-43bd-b36f-2d6606bca787.jpg?v=1761527485","url":"https:\/\/www.whiterainbookhouse.com\/products\/statistical-mechanics-and-stability-of-earl-prohofsky-9780521451840","provider":"WR Book House","version":"1.0","type":"link"}