{"product_id":"systems-biology-of-cell-signaling-james-e-ferrell-9780815346036","title":"Systems Biology of Cell Signaling: Recurring Themes and Quantitative Models","description":"\u003cp\u003eHow can we understand the complexity of genes, RNAs, and proteins and the associated regulatory networks? One approach is to look for recurring types of dynamical behavior. Mathematical models prove to be useful, especially models coming from theories of biochemical reactions such as ordinary differential equation models. Clever, careful experiments test these models and their basis in specific theories. This textbook aims to provide advanced students with the tools and insights needed to carry out studies of signal transduction drawing on modeling, theory, and experimentation. Early chapters summarize the basic building blocks of signaling systems: binding\/dissociation, synthesis\/destruction, and activation\/inactivation. Subsequent chapters introduce various basic circuit devices: amplifiers, stabilizers, pulse generators, switches, stochastic spike generators, and oscillators. All chapters consistently use approaches and concepts from chemical kinetics and nonlinear dynamics, including rate-balance analysis, phase plane analysis, nullclines, linear stability analysis, stable nodes, saddles, unstable nodes, stable and unstable spirals, and bifurcations. This textbook seeks to provide quantitatively inclined biologists and biologically inclined physicists with the tools and insights needed to apply modeling and theory to interesting biological processes.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eKey Features: \u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e \u003cli\u003eFull-color illustration program with diagrams to help illuminate the concepts\u003c\/li\u003e \u003cli\u003eEnables the reader to apply modeling and theory to the biological processes\u003c\/li\u003e \u003cli\u003eFurther Reading for each chapter\u003c\/li\u003e \u003cli\u003eHigh-quality figures available for instructors to download\u003c\/li\u003e\n\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e James Ferrell\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 0815346034\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9780815346036\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Garland Science\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 09\/28\/2021\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 266\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Paperback\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 1.70lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 11.00h x 8.20w x 0.50d\u003cbr\u003e\u003cbr\u003e\u003cb\u003eReview Citation(s): \u003c\/b\u003e\u003cbr\u003e\u003ci\u003eChoice\u003c\/i\u003e 02\/01\/2023\u003c\/ul\u003e","brand":"James Ferrell","offers":[{"title":"Paperback","offer_id":43986653315327,"sku":"9780815346036","price":100.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_dc6e5940-53b5-49b0-b278-55e81da31a5c.jpg?v=1683284547","url":"https:\/\/www.whiterainbookhouse.com\/products\/systems-biology-of-cell-signaling-james-e-ferrell-9780815346036","provider":"WR Book House","version":"1.0","type":"link"}