{"product_id":"techniques-to-investigate-mitochondrial-function-stefan-strack-9781493968886","title":"Techniques to Investigate Mitochondrial Function in Neurons","description":"\u003cp\u003eThis volume describes a broad spectrum of experimental approaches for investigating structure, function, and transport of neuronal mitochondria in health and disease. Most of these approaches were only recently developed and range from electron tomography-based 3D reconstruction of mitochondrial cristae to patch clamp recording from mitochondria in intact neurons. The chapters in this book cover topics such as mitochondrial proteomics, fluorescence lifetime imaging, respirometry and mitophagy, as well as optical approaches based on the use of genetically engineered fluorescent sensors for monitoring synaptic ATP and axonal ROS generation, mitochondrial Ca2+ cycling and pH changes, and mitochondrial dynamics and axonal trafficking in live neurons. Each chapter also discusses difficulties, tips, tricks, and precautions to take. \u003ci\u003eNeuromethods\u003c\/i\u003e series style chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. \u003cbr\u003e Cutting-edge and comprehensive, \u003ci\u003eTechniques to Investigate Mitochondrial Function in Neurons\u003c\/i\u003e is a valuable and useful resource for a broad range of investigators interested in the function of neuronal mitochondria in health and disease states.\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Stefan Strack\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 1493968882\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9781493968886\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Humana\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 03\/18\/2017\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 344\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Hardcover\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 1.86lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 10.00h x 7.00w x 0.81d","brand":"Stefan Strack","offers":[{"title":"Hardcover","offer_id":48088397512959,"sku":"9781493968886","price":169.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_d61283e1-7efa-468e-a062-26daf80f060c.jpg?v=1769104610","url":"https:\/\/www.whiterainbookhouse.com\/products\/techniques-to-investigate-mitochondrial-function-stefan-strack-9781493968886","provider":"WR Book House","version":"1.0","type":"link"}