{"product_id":"the-cancer-degradome-dylan-edwards-9781493938865","title":"The Cancer Degradome: Proteases and Cancer Biology","description":"Section 1: The Degradome and its analysis Chapter 1: Protease Genomics and the Cancer Degradome Xose S. Puente, Gonzalo R Ordonez \u0026amp; Carlos Lez-Ot匤 Chapter 2: The CLIP-CHIP: A focused oligonucleotide microarray platform for transcriptone analysis for the complete human and murine cancer degradomes. Rheinhild Kappelhoff, Claire H.Wilson, \u0026amp; Christopher M. Overall Chapter 3: The Hu\/Mu ProtIn chip: A custom dual-species Oligonucleotide Microarray for profiling degradome gene expression in tumours and their microenvironment Donald R.Scwartz, Kamiar Moin, Ekkehard Weber \u0026amp; Bonnie F Sloane Chapter 4: Quantitative Real-Time PCR analysis of degradome gene expression Caroline J Pennington, Robert K. Nuttall, Clara Sampieri -Ramirez, Matthew Wallard, Simon Pilgrim \u0026amp; Dylan R. Edwards Chapter 5: Identification of protease substrates by mass spectrometry approaches. Mari Enoksson, Wenhong Zhu \u0026amp; Guy Salvesen Chapter 6: Identification of protease substrates by mass spectrometry approaches - 2. Anna Prudova, Ulrich auf dem Keller \u0026amp; Christopher M. Overall Chapter 7: Activity based imaging and biochemical profiling tools for analysis of the cancer degradome. Vincent Dive, Margot Paulick, J.Oliver McIntyre, Lynn M. Matrisan \u0026amp; Matthew Bogyo. Chapter 8: Images of cleavage Kamiar Moin, Mansoureh Sameni, Christopher Jedeszko, Quanwen Li, Mary B. Olive, Raymond R. Mattingly \u0026amp; Bonnie F. Sloane Section 2: Insights into Protease function Chapter 9: Proteolytic pathways: Intersecting cascades in cancer development Nesrine I. Affara \u0026amp; Lisa M, Coussens Chapter 10: Physiological functions of plasminogen activation: Effects of gene deficiences in humans andmice Thomas H. Bugge Chapter 11: The plasminogen activation system in tissue remodelling and cancer invasion Kasper Almholt, Anna Juncker-Jensen, Kirsty Anne Green, Helene Solberg, Leif Roge Lund \u0026amp; John R mer Chapter 12: The urokinase plasminogen activator receptor as a target for cancer therapy Silvia D'Alessio \u0026amp; Francesco Blasi Chapter 13: The endocytic collagen receptor uPARAP\/Endo 180 in cancer invasion and tissue remodelling Thore Hillig, Lars H. Engelholm \u0026amp; Niels Behrendt Chapter 14: Physiological and pathological functions of type II transmembrane serine proteinases: Lessons from transgenic mouse models and human disease-associated mutations. Karin List \u0026amp; Thomas Bugge Chapter 15: Analysis of cysteine cathepsin knockout mice in cancer models Thomas Reinheckel, Vasilena Gocheva, Christoph Peters \u0026amp; Johanna A. Joyce Chapter 16: In vitro and in vivo models of angiogenesis to dissect MMP functions. Sarah Berndt, Fran輟ise Bruy鑽e, Maud Jost \u0026amp; Agn鑚 No? Chapter 17: The surface transplantation model to study the tumour-host interface Maud Jost, Silvia Vosseler, Silvia Blacher, Norbert E. Fusenig, Margareta Mueller \u0026amp; Agnes Noel Chapter 18: Unravelling the roles of proteases in cell migration in vitro and in vivo Jelena Gavrilovic \u0026amp; Xanthe Scott Chapter 19: New insights into MMP function in adipogenesis Kumari L Andarawewal \u0026amp; Marie-Christine Riol Chapter 20: TIMPs: Extracellular Modifiers in Cancer Development Aditya Murty, William Cruz-Munoz \u0026amp; Rama Khokha Section 3: The interface between Proteolysis and Cell Signalling Chapter 21: Invadopodia: Interface for Invasion Susette C Mueller, Vira V. Artym\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Dylan Edwards\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 149393886X\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9781493938865\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Springer\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 08\/23\/2016\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 926\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Paperback\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 2.97lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 9.21h x 6.14w x 1.94d","brand":"Dylan Edwards","offers":[{"title":"Paperback","offer_id":44717558563071,"sku":"9781493938865","price":219.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_691e1595-6578-4f4c-874d-45beb3e5419c.jpg?v=1705688620","url":"https:\/\/www.whiterainbookhouse.com\/products\/the-cancer-degradome-dylan-edwards-9781493938865","provider":"WR Book House","version":"1.0","type":"link"}