{"product_id":"the-hepatitis-b-and-delta-christoph-seeger-phd-9781621820888","title":"The Hepatitis B and Delta Viruses","description":"Despite the availability of an effective vaccine for hepatitis B, hundreds of millions of people worldwide are infected with the hepatitis B virus (HBV). This virus can cause serious liver damage and cancer in chronically infected patients. Hepatitis delta virus (HDV), a satellite of HBV, can exacerbate the disease. \u003cp\u003e\u003c\/p\u003eWritten and edited by experts in the field, this collection from \u003cem\u003eCold Spring Harbor Perspectives in Medicine\u003c\/em\u003e examines all aspects of HBV and HDV infections and their management. Contributors discuss the HBV and HDV life cycles, their unique characteristics (e.g., the formation of HBV cccDNA), the immune responses they elicit, and the challenges they present to the development of antiviral treatments. The molecular mechanisms that lead to liver cirrhosis and hepatocellular carcinoma are reviewed, as are factors that influence the severity of the disease. Conventional treatments (e.g., interferons), emerging therapeutic strategies, and ongoing efforts to find a cure for chronic infections are also described. \u003cp\u003e\u003c\/p\u003eThis volume includes perspectives on the origins and evolution of these viruses, historical milestones in HBV and HDV research, and insights from animal models (e.g., woodchucks). It is an essential reference for all virologists, clinical and laboratory investigators, and physicians interested in reducing the burden of liver disease caused by HBV and HDV.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Christoph Seeger Phd\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 1621820882\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9781621820888\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Cold Spring Harbor Laboratory Press\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 06\/30\/2015\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 363\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Hardcover\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 2.25lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 10.30h x 7.30w x 0.90d","brand":"Christoph Seeger Phd","offers":[{"title":"Hardcover","offer_id":46372431102207,"sku":"9781621820888","price":135.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_04d004e8-6584-4fbf-be71-2a5d630078b2.jpg?v=1732725923","url":"https:\/\/www.whiterainbookhouse.com\/products\/the-hepatitis-b-and-delta-christoph-seeger-phd-9781621820888","provider":"WR Book House","version":"1.0","type":"link"}