{"product_id":"the-mechanism-of-biochemical-action-sami-a-al-mudhaffar-prof-9781534949218","title":"The Mechanism of Biochemical Action of Thyroid Hormones: Thyroid hormones in action","description":"Inosine mono phosphate (IMP) is a precursor of the two purine nucleotides, adenosine mono phosphate (AMP) and guanosine monophosphate (GMP): IMP -----adenylosuccinate ------AMP and IMP to xanthine monophosphate (XMP)---GMP. The reaction IMP----- adenylosuccinate is catalyzed by the enzyme synthetase which was purified and IMP---XMP is catalyzed by the enzyme IMP dehydrogenase which was purified also .Adenylosuccinate synthetase of rat liver is stimulated by L-T3 but not D-T4 and the effect of other analogues paralled their in vivo effects . The enzyme IMP dehydrogenase is inhibited by thyroid hormones, but not by D-T4, and also, the effects of other analogues paralled their in vivo effects.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Sami a. Al-Mudhaffar Prof\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 1534949216\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9781534949218\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Createspace Independent Publishing Platform\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 06\/27\/2016\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 164\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Paperback\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 0.74lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 10.00h x 7.99w x 0.35d","brand":"Sami a. Al-Mudhaffar Prof","offers":[{"title":"Paperback","offer_id":48136756887807,"sku":"9781534949218","price":20.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_f47ab732-e215-42e0-b731-135917714829.jpg?v=1770164580","url":"https:\/\/www.whiterainbookhouse.com\/products\/the-mechanism-of-biochemical-action-sami-a-al-mudhaffar-prof-9781534949218","provider":"WR Book House","version":"1.0","type":"link"}