{"product_id":"updates-on-molecular-targeted-therapies-edward-pan-9783036585284","title":"Updates on Molecular Targeted Therapies for CNS Tumors","description":"\u003cp\u003eThe challenges in identifying effective therapies for CNS tumors continue to be daunting. Potentially effective targeted therapies must be able to penetrate the blood-brain barrier to reach the tumor and, in sufficient concentrations, to result in meaningful treatment responses. Moreover, molecular targets must be key drivers in the growth and progression of CNS tumors. Numerous potentially efficacious therapies have failed in randomized clinical trials due to other factors, including subclonal genetic intratumoral heterogeneity (particularly within malignant gliomas), epigenetic heterogeneity, and failure to target important factors involved in the tumor microenvironment. Developing effective targeted therapies requires a thorough fundamental understanding of the genetic and epigenetic factors driving tumor progression, the interactions between CNS tumor cells and the tumor microenvironment, and the key mechanisms of tumor treatment resistance.\u003c\/p\u003e\u003cp\u003eIn this Special Issue, experts in the field of CNS tumors will highlight the most promising molecular targets in the development of treatments for patients with CNS tumors.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Edward Pan\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 3036585281\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9783036585284\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Mdpi AG\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 08\/23\/2023\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 368\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Hardcover\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 2.18lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 9.61h x 6.69w x 1.13d","brand":"Edward Pan","offers":[{"title":"Hardcover","offer_id":47244273123583,"sku":"9783036585284","price":107.52,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_415f07d5-ac8a-40cb-9e30-3a0949d9dcf0.jpg?v=1758135351","url":"https:\/\/www.whiterainbookhouse.com\/products\/updates-on-molecular-targeted-therapies-edward-pan-9783036585284","provider":"WR Book House","version":"1.0","type":"link"}