{"product_id":"using-21st-century-science-to-national-academies-of-sciences-engineeri-9780309453486","title":"Using 21st Century Science to Improve Risk-Related Evaluations","description":"\u003cp\u003eOver the last decade, several large-scale United States and international programs have been initiated to incorporate advances in molecular and cellular biology, -omics technologies, analytical methods, bioinformatics, and computational tools and methods into the field of toxicology. Similar efforts are being pursued in the field of exposure science with the goals of obtaining more accurate and complete exposure data on individuals and populations for thousands of chemicals over the lifespan; predicting exposures from use data and chemical-property information; and translating exposures between test systems and humans.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eUsing 21st Century Science to Improve Risk-Related Evaluations\u003c\/i\u003e makes recommendations for integrating new scientific approaches into risk-based evaluations. This study considers the scientific advances that have occurred following the publication of the NRC reports \u003ci\u003eToxicity Testing in the 21st Century: A Vision and a Strategy\u003c\/i\u003e and \u003ci\u003eExposure Science in the 21st Century: A Vision and a Strategy.\u003c\/i\u003e Given the various ongoing lines of investigation and new data streams that have emerged, this publication proposes how best to integrate and use the emerging results in evaluating chemical risk. \u003ci\u003eUsing 21st Century Science to Improve Risk-Related Evaluations\u003c\/i\u003e considers whether a new paradigm is needed for data validation, how to integrate the divergent data streams, how uncertainty might need to be characterized, and how best to communicate the new approaches so that they are understandable to various stakeholders.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e National Academies of Sciences Engineeri,Division on Earth and Life Studies,Board on Environmental Studies and Toxic\u003cbr\u003e\u003cb\u003eISBN-10:\u003c\/b\u003e 0309453488\u003cbr\u003e\u003cb\u003eISBN-13:\u003c\/b\u003e 9780309453486\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e National Academies Press\u003cbr\u003e\u003cb\u003eLanguage:\u003c\/b\u003e English\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 03\/16\/2017\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 200\u003cbr\u003e\u003cb\u003eFormat:\u003c\/b\u003e Paperback\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 1.15lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 10.90h x 8.50w x 0.50d","brand":"National Academies of Sciences Engineeri","offers":[{"title":"Paperback","offer_id":48447693947135,"sku":"9780309453486","price":79.0,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/2982\/9887\/files\/img_014ce7d0-0c13-4d8c-aa53-0887441c668b.jpg?v=1777234179","url":"https:\/\/www.whiterainbookhouse.com\/products\/using-21st-century-science-to-national-academies-of-sciences-engineeri-9780309453486","provider":"WR Book House","version":"1.0","type":"link"}