A Dissertation Report on Tuberculosis Immunology (Paperback) (ISBN-13: 9783639343854)

Tuberculosis (TB) is the major cause of death worldwide. The enormity of the problem has been further worsened by the emergence of multi-drug resistant (MDR) strains and the dual infection with HIV. A newly identified TB threat which leaves patients virtually untreatable using currently available anti-TB drugs is XDR-TB. Protein extracted from whole cell lysate (WCL) during late log growth phase often considered candidate components for diagnosis of Tuberculosis and vaccine.In any cell proteins are ultimately working moiety, therefore proteomic analysis and seroreactivity in relation to identify a molecule could be much informative. This study includes the analysis and comparison of whole cell lysate proteins of two clinical isolates with M. tuberculosis H37Rv strain and their reactivity for searching a immunodominant antigen. Present study suggest that current clinical isolate of M. tuberculosis might be valuable to characteristics some unique dominant targets for tuberculosis diagnosis and for vaccine candidate.

Author: Gaurav Sharma, Beenu Joshi
ISBN-10: 3639343859
ISBN-13: 9783639343854
Publisher: VDM Verlag
Language: English
Published: 03/28/2011
Pages: 104
Format: Paperback
Weight: 0.36lbs
Size: 9.00h x 6.00w x 0.25d