A Review Book on Heterocycle Synthesis (Paperback) (ISBN-13: 9786206143727)

Heteroatoms constitute a very common fragment of a number of active pharmaceutical ingredients as well as excipients; from the point of view of significance, it is all the same if these are isosterically/bioisosterically replaced carbons/carbon substructures in aliphatic structures or real heterocycles. Many heterocyclic scaffolds can be considered as privilege structures including aromatic skeletons. Most frequently, nitrogen heterocycles or various positional combinations of nitrogen atoms, sulphur, and oxygen in five- or six-membered rings/fused rings can be found. There are a number of novel pathways found for their synthesis including homogenous or heterogenous catalytic system. According to statistics, more than 85% of all biologically-active chemical entities contain a heterocycle. This fact reflects the central role of heterocycles in modern drug design therefore their synthesis is important.

Author: Bapu Thorat
ISBN-10: 6206143724
ISBN-13: 9786206143727
Publisher: LAP Lambert Academic Publishing
Language: English
Published: 02/14/2023
Pages: 368
Format: Paperback
Weight: 1.19lbs
Size: 9.00h x 6.00w x 0.82d