Acute generalized exanthematous pustulosis (Paperback) (ISBN-13: 9786208041953)

Acute generalized exanthematous pustulosis (AGEP) is a rare form of toxidermia, one of the severe cutaneous adverse drug reactions (SCAR). It is a febrile, erythematous, putular cutaneous reaction, most often caused by drugs. It may also be due to a viral infection (enterovirus: coxsackie, echovirus or cytomegalovirus), a toxic substance (mercury) or a food allergen. All ages are concerned. The drugs most often responsible are antibiotics such as beta-lactams and pristinamycin. PEAG is a model of delayed drug hypersensitivity mediated by CD8 T lymphocytes. The onset of this toxidermia is short, ranging from a few hours to a few days. Diagnosis of this dermatosis is based on clinical and para-clinical criteria. These criteria were validated by a score, established in 2001 by the European SCAR study group (EuroSCAR).Clinically, PEAG manifests as a bright red, sometimes scarlatiniform, edematous erythema, undertaking the trunk, limbs, and more particularly the axillary and inguinal folds.

Author: Anissa Zaouak,Houda Hammami,Samy Fenniche
ISBN-10: 6208041953
ISBN-13: 9786208041953
Publisher: Our Knowledge Publishing
Language: English
Published: 09/03/2024
Pages: 52
Format: Paperback
Weight: 0.20lbs
Size: 9.00h x 6.00w x 0.12d