Biochemistry, Biosynthesis and Human Diseases (Hardcover) (ISBN-13: 9783110479393)

This volume on iron-sulfur proteins includes chapters that discuss how microbes, plants, and animals synthesize these complex prosthetic groups, and why it is important to understand the chemistry and biogenesis of iron sulfur proteins. In addition to their vital importance in mitochondrial respiration, numerous iron sulfur proteins are important in maintenance of DNA integrity. Multiple rare human diseases with different clinical presentations are caused by mutations of genes in the iron sulfur cluster biogenesis pathway. Understanding iron sulfur proteins is important for understanding a rapidly expanding group of metabolic pathways important in all kingdoms of life, and for understanding processes ranging from nitrogen fixation to human disease.

Author: Tracey Rouault
ISBN-10: 3110479397
ISBN-13: 9783110479393
Publisher: de Gruyter
Language: English
Published: 09/25/2017
Pages: 491
Format: Hardcover
Weight: 2.16lbs
Size: 9.61h x 6.69w x 1.06d