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"Elaborating on the science as well as the business behind the fight against cystic fibrosis, Trivedi captures the emotions of the families, doctors, and scientists involved in the clinical trials and their 'weeping with joy' as new drugs are approved, and shows how cystic fibrosis, once a 'death sentence, ' became, for many, a manageable condition. This is a rewarding and challenging work." --Publishers Weekly
Cystic fibrosis was once a mysterious disease that killed infants and children. Now it could be the key to healing millions with genetic diseases of every type--from Alzheimer's and Parkinson's to diabetes and sickle cell anemia.
In 1974, Joey O'Donnell was born with strange symptoms. His insatiable appetite, incessant vomiting, and a relentless cough--which shook his tiny, fragile body and made it difficult to draw breath--confounded doctors and caused his parents agonizing, sleepless nights. After six sickly months, his salty skin provided the critical clue: he was one of thousands of Americans with cystic fibrosis, an inherited lung disorder that would most likely kill him before his first birthday.
The gene and mutation responsible for CF were found in 1989--discoveries that promised to lead to a cure for kids like Joey. But treatments unexpectedly failed and CF was deemed incurable. It was only after the Cystic Fibrosis Foundation, a grassroots organization founded by parents, formed an unprecedented partnership with a fledgling biotech company that transformative leaps in drug development were harnessed to produce groundbreaking new treatments: pills that could fix the crippled protein at the root of this deadly disease.
From science writer Bijal P. Trivedi, Breath from Salt chronicles the riveting saga of cystic fibrosis, from its ancient origins to its identification in the dank autopsy room of a hospital basement, and from the CF gene's celebrated status as one of the first human disease genes ever discovered to the groundbreaking targeted genetic therapies that now promise to cure it.
Told from the perspectives of the patients, families, physicians, scientists, and philanthropists fighting on the front lines, Breath from Salt is a remarkable story of unlikely scientific and medical firsts, of setbacks and successes, and of people who refused to give up hope--and a fascinating peek into the future of genetics and medicine.
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Most authentic book compilation on the Oregon Trail I ever read. The way the diaries are brought to life from over 170 years ago is a remarkable achievement. Top book of year so far for me for today June 01, 2024 review Candice
This author is a breathe of fresh air in a world of lies and coverups. He brings ancient writings and new science to bring light to mankind. In this amazing work, the well known plato stories from antiquity are now put alongside this new discovery of tablets from beginning of time. This is the most complete explanation of Atlantis every brought to the public. Shame on the governments of Egypt and the world for hiding WHO BUILT THE PHYRAMIDS OF GIZA AND THE SPHINX. Once I read this book I knew why they hid this knowledge. They don't want a population to know how great the world used to be compared to know.
Randomly stumbled upon this book and I am shocked that I haven’t heard about it before. It’s hands down the best story I’ve read in years. People need to read this book. It needs to be turned into a book. This story is just plain awsome. M
This soulful book of personal poetry brought me into the past and into the present---and into my heart.
Read the first book and this 2nd one did not disappoint! Loved every chapter. More please!