Calcium-Binding Proteins of the Ef-Hand Superfamily: From Basics to Medical Applications (Hardcover) (ISBN-13: 9781493990290)

This detailed volume explores protocols for studying the many facets of Ca^2]-imaging, Ca²⁺-signaling, and Ca²⁺-binding along with background information on the principles and application of these techniques. The content of the book delves into 48 chapters including subjects such as data analysis and modern technologies to study calcium-binding and signaling in cells, the superfamily of calcium-binding proteins characterized by the EF-hand structural motif, as well as their use as diagnostic and prognostic biomarkers in Laboratory Medicine and novel therapeutic drug targets. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and comprehensive, Calcium-Binding Proteins of the EF-Hand Superfamily: From Basics to Medical Applications presents state-of-the-art, lab-based methods and easy-to-follow protocols for daily use, making it interesting for basic and medical researchers, cell- and molecular biologists, clinicians, clinical chemists, and the diagnostic industry.


Author: Claus W. Heizmann
ISBN-10: 1493990292
ISBN-13: 9781493990290
Publisher: Humana
Language: English
Published: 02/02/2019
Pages: 779
Format: Hardcover
Weight: 3.50lbs
Size: 10.00h x 7.00w x 1.69d