Cancer Metastasis and Cancer Stem Cell/Niche (Paperback) (ISBN-13: 9781681083483)

A malignant tumor is an actively growing tissue, composed of cells derived from a single cell line that has undergone irreversible differentiation. These cells are invasive and also metastasize in the body, resulting in malignant cancer. Recent research suggests that a malignant tumor originates from cancer stem cells (CSC) accompanied with physiological niches. Cancer Metastasis and Cancer Stem Cell/Niche explains the invasiveness and metastasis of cancer cells in the light of information gained from the CSC / niche theory. Five chapters present a review on the fundamental relationships between CSCs, their niche and metastasis, the regulation of cell surface glycan expression in CSCs, tumor endothelial cells and metastasis, toll-like receptor 4 (TLR4)-mediated premetastatic microenvironment, and in surgical cancer metastasis. This monograph is intended as a primary reference on CSC research for physiologists, clinical oncologists, stem cell researchers and molecular biologists.

Author: Takanori Kawaguchi
ISBN-10: 1681083485
ISBN-13: 9781681083483
Publisher: Bentham Science Publishers
Language: English
Published: 11/04/2016
Pages: 158
Format: Paperback
Weight: 0.86lbs
Size: 10.00h x 7.00w x 0.41d