Cellular Peptidases in Immune Functions and Diseases 2 (Hardcover) (ISBN-13: 9780306463839)

Of the many special roles played by proteolytic enzymes in immune reactions, this book addresses different aspects of membrane peptidases, signal transduction via ligation of membrane peptidases (especially of dipeptidyl peptidase IV/CD26 and aminopeptidase N/CD13), and regulation of membrane peptidases in vivo and in vitro. A number of newly discovered peptidases (including cathepsin F, W and X, carboxypeptidase X, attractin) are described, with special emphasis given to the role of peptidases in immune and defense reactions and in the pathogenesis of inflammatory and other diseases, including rheumatoid arthritis, pancreatitis, multiple sclerosis, Alzheimer's disease and tumours of various origins. The focus on the involvement of a selection of proteolytic enzymes in immune reactions and diseases is a unique feature of this multifaceted work, which combines biochemical, immunological and clinical research reports with literary reviews of the field.

Author: Jürgen Langner
ISBN-10: 0306463830
ISBN-13: 9780306463839
Publisher: Springer
Language: English
Published: 05/31/2000
Pages: 522
Format: Hardcover
Weight: 2.53lbs
Size: 10.00h x 7.00w x 1.19d

Review Citation(s):
Scitech Book News 09/01/2000 pg. 58