Copy Number Variants: Methods and Protocols (Hardcover) (ISBN-13: 9781493986651)

This volume offers detailed step-by-step instructions to allow beginners and experts alike to run appropriate copy number variants (CNV) detection software on a dataset of choice and discern between false positive noise and true positive CNV signals. Chapters guide readers through single nucleotide polymorphism (SNP) chips, optical mapping assembly techniques, and current open-source programs specializing in CNV detection. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and cutting-edge, Copy Number Variants: Methods and Protocols aims to provide guidance to Bioinformaticians and Molecular Biologists who are interested in identifying copy number variants (CNV) with a wide variety of experimental media

Author: Derek M. Bickhart
ISBN-10: 1493986651
ISBN-13: 9781493986651
Publisher: Humana
Language: English
Published: 07/24/2018
Pages: 206
Format: Hardcover
Weight: 1.32lbs
Size: 10.00h x 7.00w x 0.56d