DNA Damage Recognition (Paperback) (ISBN-13: 9780367392130)

Covering an array of topics, this authoritative work summarizes recent developments, while providing timely reviews on the molecular mechanisms employed by cells to distinguish between damaged and undamaged sites and stimulate the appropriate repair pathways. Richly illustrated, this guide discusses the theoretical aspects of DNA damage recognition, exploring those that are relevant for various regulatory responses, such as transcriptional regulation or checkpoint arrest. It also details key concepts in the recognition of bulky DNA base damage, reviews the excision repair of non-bulky base damage, covers short-patch repair and the recognition and repair of single- and double-strand breaks.

Author: Wolfram Siede
ISBN-10: 0367392135
ISBN-13: 9780367392130
Publisher: CRC Press
Language: English
Published: 10/18/2019
Pages: 896
Format: Paperback
Weight: 4.55lbs
Size: 9.90h x 6.90w x 1.80d