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During evolution signal transduction pathways and organ systems have been optimised for the efficient seeking, ingestion, storing and using of energy. These signalling pathways play prominent roles in lifespan determination with insulin and related signalling pathways being prime examples. The authors consider how lifespan and healthspan can be extended through knowledge of energy metabolism with the experimental model of dietary restriction being one example. The information in this volume of ACAG will foster novel approaches and experiments for further understanding the roles of energy metabolism in aging and disease.
Author: M. P. Mattson
ISBN-10: 0444514929
ISBN-13: 9780444514929
Publisher: Elsevier Science
Language: English
Published: 12/01/2003
Pages: 226
Format: Hardcover
Weight: 1.26lbs
Size: 9.74h x 6.54w x 0.59d
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