Epigenomics: From Chromatin Biology to Therapeutics (Hardcover) (ISBN-13: 9781107003828)

Understanding mechanisms of gene regulation that are independent of the DNA sequence itself - epigenetics - has the potential to overthrow long-held views on central topics in biology, such as the biology of disease or the evolution of species. High throughput technologies reveal epigenetic mechanisms at a genome-wide level, giving rise to epigenomics as a new discipline with a distinct set of research questions and methods. Leading experts from academia, the biotechnology and pharmaceutical industries explain the role of epigenomics in a wide range of contexts, covering basic chromatin biology, imprinting at a genome-wide level, and epigenomics in disease biology and epidemiology. Details on assays and sequencing technology serve as an up-to-date overview of the available technological tool kit. A reliable guide for newcomers to the field as well as experienced scientists, this is a unique resource for anyone interested in applying the power of twenty-first-century genomics to epigenetic studies.

Author: Krishnarao Appasani
ISBN-10: 1107003822
ISBN-13: 9781107003828
Publisher: Cambridge University Press
Language: English
Published: 08/02/2012
Pages: 548
Format: Hardcover
Weight: 2.80lbs
Size: 9.70h x 7.00w x 1.20d