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This book explores a wide range of topics in exposure-response modeling, from traditional PKPD modeling to other areas in drug development and beyond. It incorporates numerous examples and software programs for implementing novel methods. The book emphasizes dose adjustment and treatment adaptation based on dynamic exposure-response models, illu
Author: Jixian Wang
ISBN-10: 036773804X
ISBN-13: 9780367738044
Publisher: CRC Press
Language: English
Published: 12/18/2020
Pages: 351
Format: Paperback
Weight: 1.19lbs
Size: 9.10h x 6.10w x 1.00d
Jixian Wang is a principal statistician at Celgene International, Switzerland. He worked on drug development for 14 years at GSK and Novartis Pharma and was an academic researcher at Edinburgh University and Dundee University, where he is still an honorary research fellow. His research interests include statistical methodology and its applications to real problems in pharmaceuticals, including exposure-safety, PKPD modeling, treatment/dose selection, health economics, benefit-risk and health technology assessments, and optimal trial design.
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