Formulation and Evaluation of Cephalexin Extended Release Tablet (Paperback) (ISBN-13: 9783848432639)

In this study, controlled release matrix tablets containing cephelexin were prepared using HPMC15 cps and Eudragit L100 in different concentration by Direct compression method. Tablets were evaluated for physical properties, Hardness, friability, weight variation and In vitro dissolution study was carried on USP II apparetus (peddle type). The best formulations selected based on above parameters were subjected for Extend release study with use of different ratio of polymer as Eudragit and HPMC .The tablets with Eudragit were found to release drug for longer duration of time as compared to formulations containing HPMC. The drug release from the tablets was sufficiently sustained.

Author: Hemendra Kumar Sharma, Sandhya Chaurasia, Suneel Kumar Vasireddy
ISBN-10: 3848432633
ISBN-13: 9783848432639
Publisher: LAP Lambert Academic Publishing
Language: English
Published: 03/07/2012
Pages: 144
Format: Paperback
Weight: 0.49lbs
Size: 9.00h x 6.00w x 0.34d