From Molecules to Medicines: Structure of Biological Macromolecules and Its Relevance in Combating New Diseases and Bioterrorism (Paperback) (ISBN-13: 9789048123384)

Preface. List of Contributors. Surface Proteins of Gram-Positive Pathogens: Using Crystallography to Uncover Novel Features in Drug and Vaccine Candidates; E.N. Baker.- The Rapid Crystallization Strategy for Structure-Based Inhibitor Design; T. Bergfors.- Fragment-Based Drug Discovery in Academia: Experiences from a Tuberculosis Programme; T. Heikkila et al.- Structural Biology Contributions to the Discovery of Drugs to Treat Chronic Myelogenous Leukemia; S.W. Cowan-Jacob et al.- Integrating Crystallography Into Early Metabolism Studies; G. Cruciani et al.- The Foundations of Protein-Ligand Interaction; G. Klebe.- Structure-Based Design of TRNA-Guanine Transglycosylase Inhibitors; G. Klebe.- Progress on New Hepatitis C Virus Targets: NS2 and NS5A; J. Marcotrigiano.- Protein Structure Modeling; N. Eswar, A. Sali.- Structural Biology and Molecular Modeling in the Design of Novel DPP-4 Inhibitors; G. Scapin.- Tools to Make 3D Structural Data More Comprehensible: Emovie & Proteopedia; E.Hodis et al.- Structural Studies on Acetylcholinesterase and Paraoxonase Directed Towards Development of Therapeutic Biomolecules for the Treatment of Degenerative Diseases and Protection against Chemical Threat Agents; J.L.Sussman, Israel Silman.- Protein Function Prediction from Structure in Structural Genomics and Its Contribution to the Study of Health and Disease; J.D. Watson, J.M. Thornton.- Crystal Structures of the 2-Adrenergic Receptor; W.I. Weis et al.- Can Structures lead to better Drugs? Lessons from Ribosome Research; A.Yonath.-

Author: Joel L. Sussman
ISBN-10: 9048123380
ISBN-13: 9789048123384
Publisher: Springer
Language: English
Published: 04/27/2009
Pages: 252
Format: Paperback
Weight: 0.84lbs
Size: 9.21h x 6.14w x 0.56d