Glycobiology of the Nervous System (Hardcover) (ISBN-13: 9783031123894)

Chapter Titles

1. Introduction to the complexity of cell surface and tissue matrix glycoconjugates
2. Cells of the central nervous system: An overview of their structure and function
3. Synthesis, processing, and function of N-glycans in N-glycoproteins
4. Synthesis of O-linked glycoconjugates in the nervous system
5. Chemistry and function of glycosaminoglycans in the nervous system
6. Structural analysis of oligosaccharides and glycoconjugates using NMR
7. Glycans and carbohydrate-binding/transforming proteins in axon physiology
8. Neurological consequences of congenital disorders of glycosylation
9. Brain O-GlcNAcylation: from molecular mechanisms to clinical phenotype
10. Ganglioside microdomains on cellular and intracellular and membranes regulate neuronal cell fate determination
11. Gangliosides and cell surface ganglioside glycohydrolases in the nervous system
12. Neuronal ganglioside and GSL metabolism in health and disease Cascades of secondary metabolic errors can generate complex pathologies (in LSDs)
13. Gangliosides in neurodegenerative diseases
14. Functional impairment of the nervous system with glycolipid deficiencies
15. Carbohydrates: binding sites and potential drug targets for neural-affecting pathogens
16. Antibodies to glycolipids in Guillain-Barré syndrome, Miller Fisher syndrome and related autoimmune neurological diseases