Green Chemistry in Drug Discovery: From Academia to Industry (Paperback) (ISBN-13: 9781071620335)

1. Green Synthesis of Common Heterocycles

Christian Sch臟er, Hyejin Cho, and B駘a T

2. Greener Methods for Amide Bond Synthesis

Nathan J. Oldenhuis, Aaron M. Whittaker, and Vy M. Dong

3. Mitsunobu Reactions in Medicinal Chemistry and Development of Practical Modifications

Tsuyoshi Taniguchi

4. Direct Nucleophilic Substitution of Alcohols by Br nsted or Lewis Acids Activation: An Update

Pier Giorgio Cozzi, Andrea Gualandi, Luca Mengozzi, Elisabetta Manoni, and Claire Margaret Wilson

5. Friedel-Crafts Reactions

Grigoriy Sereda

6. Ionic Liquids: Design and Applications

Arturo Obreg-Z橾iga and Eusebio Juaristi

Part II: Synthetic Strategy

7. Designing Efficient Cascade Reactions in Drug Discovery

Chenguang Yu, He Huang, Chunquan Sheng, and Wei Wang

Razvan Cioc, Eelco Ruijter, and Romano V.A. Orru

9. Direct C-H Functionalization Approaches to Pharmaceutically Relevant Molecules

James J. Mousseau and Antonia F. Stepan

10. C-H Activation with Photoredox Catalysis

Joel W. Beatty and Corey R.J. Stephenson

11. In Situ Protecting Groups for Chemoselective Transformations

Alan Steven

Part III: Enabling Technologies

12. Expanding the Biocatalysis Toolbox

Rajesh Kumar, Carlos A. Martinez, and John W. Wong

13. New Directions in Coupling Chemistry

Gary M. Gallego, Rebecca A. Gallego, and Paul F. Richardson

14. Flow Chemistry as an Enabling Technology for Synthetic Organic Chemistry

Nicholas E. Leadbeater

15. Reaction Optimization: A High-Throughput Experimentation Approach

Simon Berritt and Jason R. Schmink

16. Radiopharmaceutical Discovery with ¹¹CO₂-Fixation Methods Inspired by Green Chemistry

Benjamin H. Rotstein and Neil Vasdev